UBB Monoclonal Antibody

SKU: BT-MCA2743

Size:100μL

Background:This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.

Research_area:Others

Target_protein:UBB

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:3C12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:UBB

Immunogen:Purified recombinant fragment of human UBB expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):26kDa

UniProt accession:P0CG47

Synonyms:UBC, UBA52, RPS27A

GeneID:7314