UBA7 Polyclonal Antibody

SKU: E-AB-52436

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:UBA7

Target Synonym:D8;MGC12713;UBA1;ubiquitin activating enzyme E1 homolog B;UBA1B;UBA7;UBA7;ubiquitin activating enzyme E1;UBA7;Ube 1L;UBE 2;UBE1L;UBE2;Ubiquitin activating enzyme 2;Ubiquitin activating enzyme E1 homolog;Ubiquitin Activating Enzyme E1 Like;Ubiquitin activating enzyme E1 related protein;Ubiquitin-activating enzyme 7;Ubiquitin-activating enzyme E1 homolog;ubiquitin-activating enzyme-2;ubiquitin-like modifier activating enzyme 7;Ubiquitin-like modifier-activating enzyme 7

Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P41226

Accession:

Background:The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

Concentration:0.6 mg/mL

Immunogen:Fusion protein of human UBA7

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:30-1:150

Calculated MW:

ObservedMW: