UBA2 Antibody - Cat. #: CSB-PA096056

SKU: CSB-PA096056

Size :100ul

Clone Number:

Aliases:Anthracycline associated resistance ARX antibody; Anthracycline-associated resistance ARX antibody; ARX antibody; FLJ13058 antibody; HRIHFB2115 antibody; SAE 2 antibody; SAE2 antibody; SAE2_HUMAN antibody; SUMO 1 activating enzyme subunit 2 antibody; SUMO activating enzyme subunit 2 antibody; SUMO-activating enzyme subunit 2 antibody; UBA2 antibody; UBA2 ubiquitin activating enzyme E1 homolog antibody; Ubiquitin like 1 activating enzyme E1B antibody; Ubiquitin like modifier activating enzyme 2 antibody; Ubiquitin-like 1-activating enzyme E1B antibody; UBLE1B antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UBT2

Immunogen:Synthesized peptide derived from C-terminal of Human Uba2.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

Mark H. L. Lambermon, Mol. Cell. Biol., Jun 2002; 22: 4346 - 4357.
Kyoung-Seok Ryu, J. Biol. Chem., Sep 2003; 278: 36621 - 36627.
R. Jrgen Dohmen, J. Biol. Chem., Jul 1995; 270: 18099.
Yoshiaki Azuma, FASEB J, Jun 2001; 10.1096.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:UBA2

Research Areas:Cell biology