U2AF35 antibody , Cat. # FNab09138

SKU: FNab09138

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:1E9

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:U2 auxiliary factor(U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2(RNU2) small nuclear RNA auxiliary factor 1(U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.

Immunogen:U2 small nuclear RNA auxiliary factor 1

Synonyms:DKFZp313J1712, FP793, RN, RNU2AF1, U2AF1, U2AF35, U2AFBP

Observed MW:38 kDa

Uniprot ID:Q01081

Reactivity:Human

Tested Application:ELISA, WB, IHC, IP

Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:200-1:2000

Gene ID:7307

Research Area:Neuroscience, Metabolism, Epigenetics