Tyro3 Monoclonal Antibody

SKU: BT-MCA3029

Size:100μL

Background:Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.

Research_area:Signal transduction, Neuroscience

Target_protein:Tyro3

applications:WB

Reactivity:Human

Clonality:Monoclonal

Clone ID:7A10C11; 7A10G4

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:Tyro3

Immunogen:Purified recombinant fragment of Tyro3 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:Q06418

Synonyms:BYK, Brt, Dtk, RSE, Sky, Tif, FLJ16467

GeneID:7301