TTR Polyclonal Antibody

SKU: E-AB-18211

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: TTR

Target Synonym: Amyloid polyneuropathy;Amyloidosis I;ATTR;Carpal tunnel syndrome 1;CTS;CTS1;Dysprealbuminemic euthyroidal hyperthyroxinemia;Dystransthyretinemic hyperthyroxinemia;Epididymis luminal protein 111;HEL111;HsT2651;PALB;Prealbumin amyloidosis type I;Prealbumin;Prealbumin Thyroxine-binding;Senile systemic amyloidosis;TBPA;Thyroxine binding prealbumin;Transthyretin;TTHY;TTR;TTR protein

Research Areas: Cancer;Cardiovascular;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P02766

Accession:

Background: Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol,through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver,choroid plexus,retinal pigment epithelium,and pancreas.Within the CNS,TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR),hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1). In addition,positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. (22103483)

Concentration: 0.72 mg/mL

Immunogen: Fusion protein of human TTR

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 16 kDa

ObservedMW: Refer to figures