TTR Monoclonal Antibody

SKU: E-AB-22144

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: TTR Mouse (1D7)

Target Synonym: Amyloid polyneuropathy;Amyloidosis I;ATTR;Carpal tunnel syndrome 1;CTS;CTS1;Dysprealbuminemic euthyroidal hyperthyroxinemia;Dystransthyretinemic hyperthyroxinemia;Epididymis luminal protein 111;HEL111;HsT2651;PALB;Prealbumin amyloidosis type I;Prealbumin;Prealbumin Thyroxine-binding;Senile systemic amyloidosis;TBPA;Thyroxine binding prealbumin;Transthyretin;TTHY;TTR;TTR protein

Research Areas: Cancer;Cardiovascular;Neuroscience

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human

Application: WB;IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone NO.: Clone:2A4

UNIProt ID: P02766

Accession:

Background: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Concentration: 1 mg/mL

Immunogen: Recombinant Protein of TTR

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification method: Protein A purification

Dilution: WB 1:500-2000;IHC 1:50-300

Calculated MW:

ObservedMW: 16kDa