TRIP13 Antibody - Cat. #: CSB-PA623008LA01HU

SKU: CSB-PA623008LA01HU

Size :50ug

Clone Number:

Aliases:16E1-BP antibody; 16E1BP antibody; Homo sapiens HPV16 E1 protein binding protein mRNA complete cds antibody; HPV16 E1 protein binding protein antibody; HPV16 E1 protein-binding protein antibody; Human papillomavirus type 16 E1 protein binding protein antibody; Human papillomavirus type 16 E1 protein-binding protein antibody; Pachytene checkpoint protein 2 homolog antibody; PCH2 antibody; Thyroid hormone receptor interactor 13 antibody; Thyroid receptor interacting protein 13 antibody; Thyroid receptor-interacting protein 13 antibody; TR-interacting protein 13 antibody; TRIP-13 antibody; Trip13 antibody; TRP13_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15645

Immunogen:Recombinant Human Pachytene checkpoint protein 2 homolog protein (181-390AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background:Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TRIP13

Research Areas:Neuroscience