TNFSF18 Antibody - Cat. #: CSB-PA891791ESR1HU

SKU: CSB-PA891791ESR1HU

Size :50ul

Clone Number:

Aliases:Activation inducible TNF related ligand antibody; Activation-inducible TNF-related ligand antibody; AITR ligand antibody; AITRL antibody; GITR ligand antibody; GITRL antibody; Glucocorticoid induced TNF related ligand antibody; Glucocorticoid induced TNFR related protein ligand antibody; Glucocorticoid-induced TNF-related ligand antibody; hGITRL antibody; MGC138237 antibody; TL6 antibody; TNF18_HUMAN antibody; TNFSF18 antibody; TNLG2A antibody; Tumor necrosis factor (ligand) superfamily member 18 antibody; Tumor necrosis factor ligand 2A antibody; Tumor necrosis factor ligand superfamily member 18 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UNG2

Immunogen:Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein (72-199AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TNFSF18

Research Areas:Cancer; Cardiovascular; Tags & Cell Markers; Immunology; Signal transduction