TNFRSF11A Monoclonal Antibody

SKU: BT-MCA3210

Size:100μL

Background:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.

Research_area:Signal transduction, Cardiovascular, Immunology

Target_protein:TNFRSF11A

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:8H8B2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:TNFRSF11A

Immunogen:Purified recombinant fragment of human TNFRSF11A (AA: extra 30-212) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):66kDa

UniProt accession:Q9Y6Q6

Synonyms:FEO, OFE, ODFR, OSTS, PDB2, RANK, CD265, OPTB7, TRANCER, LOH18CR1

GeneID:8792