TIRAP Antibody - Cat. #: CSB-PA023570ESR1HU

SKU: CSB-PA023570ESR1HU

Size :50ul

Clone Number:

Aliases:TIRAP antibody; MAL antibody; Toll/interleukin-1 receptor domain-containing adapter protein antibody; TIR domain-containing adapter protein antibody; Adaptor protein Wyatt antibody; MyD88 adapter-like protein antibody; MyD88-2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P58753

Immunogen:Recombinant Human Toll/interleukin-1 receptor domain-containing adapter protein (1-221AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background:Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TIRAP

Research Areas:Cardiovascular; Immunology; Signal transduction