TIPIN antibody , Cat. # FNab08716

SKU: FNab08716

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.

Immunogen:TIMELESS interacting protein

Synonyms:TIPIN, FLJ20516, TIMELESS interacting protein

Observed MW:48kd

Uniprot ID:Q9BVW5

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:200-1:2000

Gene ID:54962

Research Area:Epigenetics