TIN2 Polyclonal Antibody

SKU: BT-AP09039

Size:100μL

Background:TINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:TINF2

applications:WB, IHC-p, ELISA

Reactivity:Human

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:TIN2 Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):50023

UniProt accession:Human: Q9BSI4; Mouse: Q9QXG9

Synonyms:TINF2; TIN2; TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2

GeneID:Human: 26277