TIAM2 Antibody - Cat. #: CSB-PA818235LA01HU

SKU: CSB-PA818235LA01HU

Size :50ug

Clone Number:

Aliases:FLJ41865 antibody; OTTHUMP00000017472 antibody; SIF and TIAM1 like exchange factor antibody; SIF and TIAM1-like exchange factor antibody; STEF antibody; T cell lymphoma invasion and metastasis 2 antibody; T lymphoma invasion and metastasis inducing protein 2 antibody; T-lymphoma invasion and metastasis-inducing protein 2 antibody; TIAM 2 antibody; TIAM-2 antibody; Tiam2 antibody; TIAM2_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8IVF5

Immunogen:Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2 protein (1500-1627AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

Background:Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane (By similarity). Activates specifically RAC1, but not CDC42 and RHOA.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TIAM2

Research Areas:Signal transduction