TIA1 Monoclonal Antibody

SKU: BT-MCA2012

Size:100μL

Background:The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene.

Research_area:Epigenetics and nuclear signaling, Cancer, Cell biology, Immunology

Target_protein:TIA1

applications:IHC, ICC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:3A3B9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:TIA1

Immunogen:Purified recombinant fragment of human TIA1 (AA: 1-215) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):43kDa

UniProt accession:P31483

Synonyms:WDM, TIA-1

GeneID:7072