THOC7 Antibody - Cat. #: CSB-PA746911LA01HU

SKU: CSB-PA746911LA01HU

Size :50ug

Clone Number:

Aliases:FLJ23445 antibody; fSAP24 antibody; Functional spliceosome associated protein 24 antibody; Functional spliceosome-associated protein 24 antibody; hTREX30 antibody; Ngg1 interacting factor 3 like 1 binding protein 1 antibody; Ngg1 interacting factor 3 like protein 1 binding protein 1 antibody; Ngg1-interacting factor 3-like protein 1-binding protein 1 antibody; NIF3L1 binding protein 1 antibody; NIF3L1-binding protein 1 antibody; NIF3L1BP1 antibody; THO complex 7 homolog (Drosophila) antibody; THO complex 7 homolog antibody; THO complex subunit 7 homolog antibody; THOC 7 antibody; thoc7 antibody; THOC7_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6I9Y2

Immunogen:Recombinant Human THO complex subunit 7 homolog protein (4-204AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:THOC7

Research Areas:Epigenetics and Nuclear Signaling