THBD Antibody - Cat. #: CSB-PA179250

SKU: CSB-PA179250

Size :100ul

Clone Number:

Aliases:AHUS 6 antibody; AHUS6 antibody; BDCA 3 antibody; BDCA3 antibody; CD 141 antibody; CD141 antibody; CD141 antigen antibody; Fetomodulin antibody; Thbd antibody; THPH12 antibody; THRM antibody; Thrombomodulin antibody; TM antibody; TRBM_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P07204

Immunogen:Synthesized peptide derived from C-terminal of Human THBD.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Suzuki K., EMBO J. 6:1891-1897(1987).
Wen D., Biochemistry 26:4350-4357(1987). Jackman R.W., Proc. Natl. Acad. Sci. U.S.A. 84:6425-6429(1987).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:THBD

Research Areas:Cardiovascular;Stem cells