TCHP Antibody, HRP conjugated - Cat. #: CSB-PA874804LB01HU

SKU: CSB-PA874804LB01HU

Size :50ug

Clone Number:

Aliases:TCHP antibody; Trichoplein keratin filament-binding protein antibody; Protein TCHP antibody; Mitochondrial protein with oncostatic activity antibody; Mitostatin antibody; Tumor suppressor protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9BT92

Immunogen:Recombinant Human Trichoplein keratin filament-binding protein (1-498AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a \'capping\' or \'branching\' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (PubMed:15731013, PubMed:18931701). Is a negative regulator of ciliogenesis (PubMed:25270598).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TCHP

Research Areas:Others