Tau(Phospho-Ser416) Rabbit Polyclonal Antibody

SKU: BT-AP05027

Size:100μL

Background:This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex| regulated alternative splicing| giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system| depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease| Pick's disease| frontotemporal dementia| cortico-basal degeneration and progressive supranuclear palsy.

Research_area:Neuroscience ; Signal transduction

Target_protein:MAPT

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Tau

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P10636; Mouse: P10637; Rat: P19332

Synonyms:Tau ;Ser416 ; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau

GeneID:Human: 4137; Mouse: 17762