Syk(Phospho Tyr348) Polyclonal Antibody

SKU: BT-AP14610

Size:100μL

Background:This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area:Cardiovascular; Signal transduction; Immunology

Target_protein:SYK

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat, Monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Tyrosine-protein kinase SYK

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):72066

UniProt accession:Human: P43405; Mouse: P48025; Rat: Q64725

Synonyms:Tyrosine-protein kinase SYK; SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk

GeneID:Human: 6850; Mouse: 20963; Rat: 25155