SQSTM1 Monoclonal Antibody

SKU: BT-MCA4761

Size:100μL

Background:This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Research_area:Epigenetics and nuclear signaling, Cancer, Signal transduction, Cardiovascular, Metabolism

Target_protein:SQSTM1

applications:WB, IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5H7E2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SQSTM1

Immunogen:Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):47.7kDa

UniProt accession:Q13501

Synonyms:p60, p62, A170, OSIL, PDB3, ZIP3, p62B

GeneID:8878