SOX2 Monoclonal Antibody

SKU: BT-MCA2801

Size:100μL

Background:SOX2: SRY (sex determining region Y)-box 2. Entrez Protein NP_003097. It is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Research_area:Epigenetics and nuclear signaling, Neuroscience, Developmental biology, Stem cells

Target_protein:SOX2

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:10F10C9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SOX2

Immunogen:Purified recombinant fragment of SOX2 (aa1-170) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):34.3kDa

UniProt accession:P48431

Synonyms:ANOP3, MCOPS3, MGC2413

GeneID:6657