SMAGP rabbit pAb

SKU: ES11260

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Rat;Mouse

Dilution:WB 1:500-2000 ELISA 1:5000-20000

Immunogen:Synthesized peptide derived from human protein . at AA range: 30-110

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):10kD

Human_gene_id:57228

Human_swiss_prot_no:Q0VAQ4

Subcellular_location:Cell membrane ; Single-pass type III membrane protein . Cytoplasmic vesicle membrane ; Single-pass type III membrane protein . Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913). Detected on cytoplasmic membranes in undifferentiated tumors (PubMed:15986429). .

Other_name:

Background:function:May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.,PTM:O-glycosylated. The O-glycan is modified with sialic acid residues.,similarity:Belongs to the SMAGP family.,subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors.,tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level).,