SLIT2 Polyclonal Antibody

SKU: E-AB-13664

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: SLIT2

Target Synonym: Drad 1;E030015M03Rik;E130320P19Rik;FLJ14420;OTTHUMP00000158695;OTTHUMP00000217852;OTTHUMP00000217853;OTTHUMP00000217854;Slil 3;Slil3;Slit 2;Slit homolog 2 (Drosophila);Slit homolog 2;Slit homolog 2 protein;Slit homolog 2 protein C-product;Slit-2;Slit2;SLIT2

Research Areas: Cancer;Neuroscience

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O94813

Accession:

Background: Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.

Concentration: 0.3 mg/mL

Immunogen: Synthetic peptide of human SLIT2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:25-1:100

Calculated MW: 170kDa

ObservedMW: