SLIT2 Antibody - Cat. #: CSB-PA245341

SKU: CSB-PA245341

Size :50ul

Clone Number:

Aliases:Drad 1 antibody; E030015M03Rik antibody; E130320P19Rik antibody; FLJ14420 antibody; OTTHUMP00000158695 antibody; OTTHUMP00000217852 antibody; OTTHUMP00000217853 antibody; OTTHUMP00000217854 antibody; Slil 3 antibody; Slil3 antibody; Slit 2 antibody; Slit homolog 2 (Drosophila) antibody; Slit homolog 2 antibody; Slit homolog 2 protein antibody; Slit homolog 2 protein C-product antibody; Slit-2 antibody; Slit2 antibody; SLIT2_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O94813

Immunogen:Synthetic peptide of Human SLIT2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Background:Secreted leucine-rich repeat-containing proteins 1-3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural development by acting as high-affinity signaling ligands for the repulsive guidance receptor, Roundabout (Robo. Within the developing central nervous system (CNS) of different vertebrate systems, Slit proteins are expressed in equivalent regions, suggesting a conserved function among vertebrate homologs. Slit is expressed in the midline of the central nervous system in both vertebrates and invertebrates, where it functions as a regulatory factor of mesodermal cell movement during gastrulation. Slit2 is a short range inhibitory guidance cue for retinal ganglion cell (RGC) axons that may mediate spatial progression of RGCs.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SLIT2

Research Areas:Neuroscience;Signal transduction