SLC4A4 Antibody - Cat. #: CSB-PA773563

SKU: CSB-PA773563

Size :50ul

Clone Number:

Aliases:DKFZp781H1314 antibody; Electrogenic sodium bicarbonate cotransporter 1 antibody; hhNMC antibody; HNBC 1 antibody; HNBC1 antibody; kNBC 1 antibody; KNBC antibody; kNBC1 antibody; Na(+)/HCO3(-) cotransporter antibody; Na+HCO3- cotransporter 4 antibody; NBC 1 antibody; NBC 2 antibody; NBC1 antibody; NBC2 antibody; Nbc4 antibody; NBCE 1 antibody; NBCE1 antibody; OTTHUMP00000160355 antibody; OTTHUMP00000218884 antibody; OTTHUMP00000218885 antibody; PNBC antibody; S4A4_HUMAN antibody; SLC4A4 antibody; SLC4A5 antibody; Sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney, sodium bicarbonate cotransporter, pancreas) antibody; Sodium bicarbonate cotransporter antibody; Sodium bicarbonate cotransporter kidney antibody; sodium bicarbonate cotransporter member 4 antibody; Sodium bicarbonate cotransporter pancreas antibody; Solute carrier family 4 member 4 antibody; Solute carrier family 4 sodium bicarbonate cotransporter member 4 antibody; Solute carrier family 4 sodium bicarbonate cotransporter member 5 antibody; Solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y6R1

Immunogen:Fusion protein of Human SLC4A4

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene. Sodium bicarbonate cotransporters (NBCs) mediate the coupled movement of sodium and bicarbonate ions across the plasma membrane of many cells. This is an electrogenic process with an apparent stoichiometry of 3 bicarbonate ions per sodium ion. Sodium bicarbonate cotransport is involved in bicarbonate secretion/absorption and intracellular pH regulation. Romero and Boron (1999) reviewed NBCs. Soleimani and Burnham (2000) reviewed NBCs and their regulation in physiologic and pathophysiologic states.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SLC4A4

Research Areas:Neuroscience;Metabolism;Signal transduction