SIX5 Antibody - Cat. #: CSB-PA103371

SKU: CSB-PA103371

Size :100ul

Clone Number:

Aliases:SIX5 antibody; DMAHP antibody; Homeobox protein SIX5 antibody; DM locus-associated homeodomain protein antibody; Sine oculis homeobox homolog 5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8N196

Immunogen:Synthesized peptide derived from internal of Human SIX5.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter By similarity. Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 By similarity.

Boucher C.A., Hum. Mol. Genet. 4:1919-1925(1995).
Grimwood J., Nature 428:529-535(2004).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SIX5

Research Areas:Epigenetics and Nuclear Signaling