SIRT3 Antibody - Cat. #: CSB-PA229200

SKU: CSB-PA229200

Size :100ul

Clone Number:

Aliases:hSIRT 3 antibody; hSIRT3 antibody; Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase antibody; NAD dependent deacetylase sirtuin 3 mitochondrial antibody; NAD-dependent protein deacetylase sirtuin-3, mitochondrial antibody; Regulatory protein SIR2 homolog 3 antibody; Silent mating type information regulation 2 S.cerevisiae homolog 3 antibody; Sir 2 like 3 antibody; SIR 2 like protein 3 antibody; SIR 3 antibody; SIR2 L3 antibody; Sir2 like 3 antibody; SIR2 like protein 3 antibody; SIR2-like protein 3 antibody; SIR2L3 antibody; SIR3_HUMAN antibody; SIRT 3 antibody; SIRT3 antibody; Sirtuin 3 antibody; Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae) antibody; Sirtuin type 3 antibody; Sirtuin3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NTG7

Immunogen:Synthesized peptide derived from C-terminal of Human SIRT3.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.

Bechtel S., BMC Genomics 8:399-399(2007).
Schwer B., J. Cell Biol. 158:647-657(2002).
Onyango P., Proc. Natl. Acad. Sci. U.S.A. 99:13653-13658(2002).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SIRT3

Research Areas:Epigenetics and Nuclear Signaling;Cancer?Cardiovascular?Cell biology;Metabolism