GeneBio Systems
SIA7D rabbit pAb
SIA7D rabbit pAb
SKU:ES13110
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Size: 100μL
Source:Rabbit
Applications:WB
Reactivity:Human; Mouse
Dilution:WB 1:500-2000
Immunogen:Synthesized peptide derived from human SIA7D AA range: 194-244
Storage_stability:-20°C/1 year
Clonality:Polyclonal
Isotype:IgG
Concentration:1 mg/ml
Observed_band(KD):
Human_gene_id:27090
Human_swiss_prot_no:Q9H4F1
Subcellular_location:Golgi apparatus membrane ; Single-pass type II membrane protein .
Other_name:
Background:The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein prefers glycoproteins rather than glycolipids as substrates and shows restricted substrate specificity, utilizing only the trisaccharide sequence Neu5Ac-alpha-2,3-Gal-beta-1,3-GalNAc. In addition, it is involved in the synthesis of ganglioside GD1A from GM1B. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
