SGK1 Monoclonal Antibody

SKU: E-AB-22207

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: SGK1 Mouse (4D12)

Target Synonym: OTTHUMP00000017247;Serine/threonine protein kinase SGK;Serine/threonine protein kinase Sgk1;Serine/threonine-protein kinase Sgk1;Serum and glucocorticoid regulated kinase;Serum/glucocorticoid regulated kinase 1;Serum/glucocorticoid regulated kinase;Serum/glucocorticoid-regulated kinase 1;SGK 1;SGK;SGK1;Sgk1 variant i3;SGK1

Research Areas: Cancer;Developmental Biology;Signal Transduction;Stem Cells

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human;Mouse;Rat

Application: IHC-p

Isotype: IgG

Clonality: Monoclonal

Clone NO.: Clone:4D12

UNIProt ID: O00141

Accession:

Background: Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, KCNA3/Kv1.3 or EAAT1. Isoform 2 exhibited a greater effect on cell plasma membrane expression of ENaC and Na(+) transport than isoform 1.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide of SGK1

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Protein A purification

Dilution: IHC 1:100-200

Calculated MW:

ObservedMW: