SERPINE1 Monoclonal Antibody

SKU: BT-MCA3554

Size:100μL

Background:This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area:Cardiovascular

Target_protein:SERPINE1

applications:IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:1D5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:SERPINE1

Immunogen:Purified recombinant fragment of human SERPINE1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):45kDa

UniProt accession:P05121

Synonyms:PAI, PAI1, PAI-1, PLANH1

GeneID:5054