S100A1 Antibody - Cat. #: CSB-PA224994

SKU: CSB-PA224994

Size :100ul

Clone Number:

Aliases:Bpb antibody; NEF antibody; Protein S100-A1 antibody; S-100 protein alpha chain antibody; S-100 protein subunit alpha antibody; S100 alpha antibody; S100 beta antibody; S100 calcium binding protein A1 antibody; S100 calcium binding protein B antibody; S100 calcium-binding protein A1 antibody; S100 protein alpha polypeptide antibody; S100A antibody; s100a1 antibody; S100B antibody; S100beta antibody; S10A1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P23297

Immunogen:Synthesized peptide derived from Human S100 A1.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

Background:Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Patrick Most, J. Biol. Chem., Nov 2003; 278: 48404 - 48412.
Miki Okada, J. Biol. Chem., Feb 2004; 279: 4221 - 4233.
Melanie Boerries, Mol. Cell. Biol., Jun 2007; 27: 4365 - 4373.
Patrick Most, J. Clin. Invest., Dec 2004; 114: 1550 - 1563.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:S100A1

Research Areas:Epigenetics and Nuclear Signaling;Cell biology