RTN3 Monoclonal Antibody

SKU: BT-MCA2524

Size:100μL

Background:RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.

Research_area:Cell Biology, Signal Transduction, Metabolism, Cancer

Target_protein:RTN3

applications:ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:1E11

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:RTN3

Immunogen:Purified recombinant fragment of RTN3 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):113kDa

UniProt accession:O95197

Synonyms:HAP, ASYIP, NSPL2, NSPLII, RTN3-A1

GeneID:10313