RPRD1B Antibody, FITC conjugated - Cat. #: CSB-PA878854HC01HU

SKU: CSB-PA878854HC01HU

Size :50ug

Clone Number:

Aliases:RPRD1B antibody; C20orf77 antibody; CREPT antibody; Regulation of nuclear pre-mRNA domain-containing protein 1B antibody; Cell cycle-related and expression-elevated protein in tumor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NQG5

Immunogen:Recombinant Human Regulation of nuclear pre-mRNA domain-containing protein 1B protein (2-172AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3\' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RPRD1B

Research Areas:Cell biology