RPGF2 Polyclonal Antibody

SKU: BT-AP13914

Size:100μL

Background:Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000

Research_area:Neuroscience; Signal transduction

Target_protein:RAPGEF2

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Rap guanine nucleotide exchange factor 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9Y4G8; Mouse: Q8CHG7; Rat: F1M386

Synonyms:Rap guanine nucleotide exchange factor 2 ;Neural RAP guanine nucleotide exchange protein;nRap GEP;PDZ domain-containing guanine nucleotide exchange factor 1;PDZ-GEF1;RA-GEF

GeneID:Human: 9693