RNF7 antibody , Cat. # FNab07361

SKU: FNab07361

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Probable component of the SCF(SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.

Immunogen:ring finger protein 7

Synonyms:RBX2, ROC2, SAG

Observed MW:13 kDa

Uniprot ID:Q9UBF6

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IF

Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200

Gene ID:9616

Research Area:Cell Division and Proliferation, Metabolism