RN103 Rabbit Polyclonal Antibody

SKU: BT-AP04493

Size:100μL

Background:The protein encoded by this gene contains a RING-H2 finger| a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum| but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment| suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene.

Research_area:Epigenetics and nuclear signaling

Target_protein:RNF103

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:RN103

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):75350

UniProt accession:Human: O00237; Mouse: Q9R1W3; Rat: Q9EPZ8

Synonyms:RN103

GeneID:Human: 7844; Mouse: 22644