RhoA(Phospho Ser188) Rabbit Polyclonal Antibody

SKU: BT-AP04463

Size:100μL

Background:This gene encodes a member of the Rho family of small GTPases| which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape| attachment| and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.

Research_area:Cancer; Signal transduction

Target_protein:RHOA

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:RhoA

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):21230

UniProt accession:Human: P61586; Mouse: Q9QUI0; Rat: P61589

Synonyms:RhoA ;Phospho Ser188; Transforming protein RhoA; Rho cDNA clone 12; h12

GeneID:Human: 387; Mouse: 11848; Rat: 117273