RELN rabbit pAb

SKU: ES10146

Size: 100μL

Source:Rabbit

Applications:IHC;IF

Reactivity:Human;Rat

Dilution:IHC-p 1:50-300

Immunogen:Synthesized peptide derived from human protein . at AA range: 270-350

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):380kD

Human_gene_id:5649

Human_swiss_prot_no:P78509

Subcellular_location:Secreted, extracellular space, extracellular matrix .

Other_name:

Background:This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008],