Recombinant xCT Monoclonal Antibody

SKU: AN301376L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:xCT

Target Synonym:CCBR;SLC7A;SLC7A11;CCBR1;xCT;(cationic amino acid transporter;Amino acid transport system xc-;Amino acid transport system xc xCT;Calcium channel blocker resistance protein CCBR1;Cysteine/glutamate transporter;Cystine/glutamate transporter;member 11;OTTHUMP00000164578;solute carrier family 7;Solute carrier family 7 (anionic amino acid transporter light chain;Solute carrier family 7 member 11;SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN;xc- system);y+ system) member 11;SLC7A11

Research Areas:Signal Transduction;Cell Biology;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6F6

UNIProt ID:Q9UPY5

Accession:

Background:This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human xCT protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:37 kDa

ObservedMW:55 kDa