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GeneBio Systems

Recombinant Wilms Tumor Protein Monoclonal Antibody

Recombinant Wilms Tumor Protein Monoclonal Antibody

AN300904L

€296,95 EUR
€296,95 EUR
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Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Wilms Tumor Protein

Target Synonym:AWT;FWT;NPHS;EWS-WT;WIT;WT1;AWT1;EWS-WT1;GUD;NPHS4;WAGR;WIT-2;WT33;FWT1;Wilms Tumor;Wilms tumor 1;Wilms' tumor gene;Wilms tumor protein;Wilms' tumor protein;WIT 2;WIT2;WT;WT 1;WIT 2; WT 1;AWT1;FWT1;GUD;NPHS4;WAGR;Wilms tumor 1;Wilms Tumor;Wilms tumor protein;Wilms' tumor gene;Wilms' tumor protein;WIT2;WT;WT1;WT1;WT33;Wilms' Tumor 1

Research Areas:Tags & Cell Markers;Epigenetics and Nuclear Signaling;Cancer;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:8C5

UNIProt ID:P19544

Accession:

Background:This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Wilms Tumor Protein protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:55 kDa

ObservedMW:55 kDa

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