Recombinant Transmembrane Protein 173 Monoclonal Antibody

SKU: E-AB-81615

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:Transmembrane Protein 173

Target Synonym:endoplasmic reticulum IFN stimulator;Endoplasmic reticulum interferon stimulator;ERIS;FLJ38577;hMITA;hSTING;Mediator of IRF3 activation;MITA;Mitochondrial mediator of IRF3 activation;MPYS;N terminal methionine proline tyrosine serine plasma membrane tetraspanner;NET23;Stimulator of interferon genes;Stimulator of interferon genes protein;STING;TM173;Tmem173;Transmembrane protein 173

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat

Application:WB;IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:R06-9A7

UNIProt ID:Q86WV6

Accession:

Background:This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Concentration:300 μg/mL

Immunogen:Recombinant protein of human TMEM173

Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Purification method:Affinity Purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100

Calculated MW:42kDa

ObservedMW:40kDa