Recombinant TNF α Monoclonal Antibody

SKU: AN300877L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:TNF α

Target Synonym:Tumor Necrosis Factor Ligand Superfamily Member;TNFSF;TNF;DIF;TNF-alpha;TNFA;TNFSF2;TNLG1F;TNF alpha;Cachectin;Tumor Necrosis Factor;Tumor Necrosis Factor Ligand Superfamily Member 2;TNF-a;APC1;APC1 protein;DIF、TNF-alpha、TNFA、TNFSF2;Differentiation inducing factor;Macrophage cytotoxic factor;macrophage derived;member 2;Membrane Form;monocyte derived;soluble form;sTNFA;TNF superfamily;Tumor necrosis factor alpha;TNFA

Research Areas:Immunology;Signal Transduction;Cancer;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4D8

UNIProt ID:P01375

Accession:

Background:This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human TNF α protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:26 kDa

ObservedMW:18 kDa