Recombinant TGF β Receptor II Monoclonal Antibody

SKU: AN301373L

Size::

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:TGF β Receptor II

Target Synonym:MFS;LDS;FAA;AAT;TAAD;TGFR;TGF-beta receptor type;TGFBR;AAT3;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;TGFR-2;TGFbeta-RII;TGF beta Receptor II;TGFBR2;TGF-beta receptor type-2;TGF-beta type II receptor;Transforming growth factor-beta receptor type II;FAA3;LDS1B;LDS2;LDS2B;MFS2;RIIC;TAAD2;Tgfbr2;beta receptor II (70/80kDa);beta receptor II alpha;beta receptor II beta;beta receptor II delta;beta receptor II epsilon;beta receptor II gamma;TbetaR II;TbetaR-II;TBRII;TBR-ii;TGF beta receptor type 2;TGF beta receptor type II;TGF beta receptor type IIB;TGF beta type II receptor;TGFB R2;TGFbeta - RII;TGF-beta receptor type II;TGFbeta RII;TGF-beta-R2;TGFR2;Transforming growth factor;transforming growth factor beta receptor 2;Transforming growth factor beta receptor II;Transforming growth factor beta receptor type II;Transforming growth factor beta receptor type IIC

Research Areas:Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6F2

UNIProt ID:P37173

Accession:

Background:This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human TGF β Receptor II protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:65 kDa

ObservedMW:65 kDa