Recombinant SOD2 (Acetyl Lys68) Monoclonal Antibody

SKU: AN301412L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies;Acetyl/Phospho/Methyl Antibodies

Abbreviation:SOD2 (Acetyl Lys68)

Target Synonym:SOD;MVCD;superoxide dismutase;IPO-B;IPOB;MNSOD;MVCD6;Mn-SOD;SOD2;Superoxide Dismutase [Mn] Mitochondrial;superoxide dismutase 2;IPOB;IPO-B;MNSOD;Mn-SOD;MVCD6;superoxide dismutase 2;EC:1.15.1.1;mitochondrial;Superoxide dismutase [Mn]

Research Areas:Cell Biology;Signal Transduction;Neuroscience;Cardiovascular;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A107

UNIProt ID:P04179

Accession:

Background:Manganese superoxide dismutase (MnSOD), also named as SOD2, is a mitochondrial detoxification enzyme that catalyzes the conversion of superoxide to hydrogen peroxide. Hydrogen peroxide is then decomposed to water by catalase, glutathione peroxidase, or peroxiredoxins. MnSOD and other enzymes involved in antioxidant defense protect cells from reactive oxygen species (ROS). Calorie restriction leads to SIRT3-mediated deacetylation of MnSOD and the subsequent increase of its antioxidant activity. MnSOD also plays an essential role in mediating the protective effect of mTOR inhibition to reduce epithelial stem cell senescence.

Concentration:1 mg/mL

Immunogen:Acetylated human histone SOD2 (Lys68) peptide

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100

Calculated MW:25 kDa

ObservedMW:20 kDa