Recombinant SIRT3 Monoclonal Antibody

SKU: AN300974L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:SIRT3

Target Synonym:SIRT;SIR2L;sirtuin;SIRT3;SIR2L3;sirtuin 3;SIR2L3;sirtuin 3;hSIRT 3;hSIRT3;mitochondrial;Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase;NAD dependent deacetylase sirtuin 3 mitochondrial;NAD-dependent protein deacetylase sirtuin-3;Regulatory protein SIR2 homolog 3;Silent mating type information regulation 2 S.cerevisiae homolog 3;Sir 2 like 3;SIR 2 like protein 3;SIR 3;SIR2 L3;Sir2 like 3;SIR2 like protein 3;SIR2-like protein 3;SIR3;SIRT 3;Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae);Sirtuin type 3;Sirtuin3

Research Areas:Epigenetics and Nuclear Signaling;Cell Biology;Cancer;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:10A9

UNIProt ID:Q9NTG7

Accession:

Background:This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human SIRT3 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:1000-1:5000

Calculated MW:44 kDa

ObservedMW:28 kDa