Recombinant SIRT2 Monoclonal Antibody

SKU: AN301727L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:SIRT2

Target Synonym:SIR;SIRT;sirtuin;SIRT2;SIR2;SIR2L;SIR2L2;sirtuin 2;NAD-dependent protein deacetylase sirtuin-2;Regulatory protein SIR2 homolog 2;SIR2-like protein 2;Sirtuin type 2

Research Areas:Epigenetics and Nuclear Signaling;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A435

UNIProt ID:Q8IXJ6

Accession:

Background:NAD-dependent protein deacetylase sirtuin-2 (SIRT2) is a NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors. SIRT2 participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. SIRT2 plays a major role in the control of cell cycle progression and genomic stability. It also functions in the antephase checkpoint preventing precocious mitotic entry in response to microtubule stress agents, and hence allowing proper inheritance of chromosomes.

Concentration:1 mg/mL

Immunogen:Recombinant human SIRT2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100

Calculated MW:43 kDa

ObservedMW:36, 43 kDa