Recombinant SIGNR1/CD209b Monoclonal Antibody

SKU: AN300523P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:CD209B

Target Synonym:OtB;DC-SIGN-related protein;DC-SIGNR;CD209;CD209 antigen-like protein B;DC-SIGNR1;DC-SIGN-related protein 1;OtB7;Cd209b

Research Areas:

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Mouse

Application:ICC/IF

Isotype:IgG

Clonality:Monoclonal

Clone NO.:8A1

UNIProt ID:Q8CJ91

Accession:

Background:CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Concentration:1 mg/mL

Immunogen:Recombinant Mouse SIGNR1/CD209b protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:20-1:100

Calculated MW:

ObservedMW: