Recombinant REG4 Monoclonal Antibody

SKU: AN300226P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:REG4

Target Synonym:REG;Regenerating islet-derived protein;REG4;GISP;REG-IV;RELP;Gastrointestinal secretory protein;Regenerating islet-derived protein 4;Regenerating islet-derived protein IV;REG-like protein;regenerating family member 4

Research Areas:Immunology;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:7A10

UNIProt ID:Q9BYZ8

Accession:

Background:Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.

Concentration:1 mg/mL

Immunogen:Recombinant Human REG4 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;

Calculated MW:

ObservedMW: