Recombinant QSOX1 Monoclonal Antibody

SKU: AN301645L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:QSOX1

Target Synonym:UNQ;PRO;QSOX;QSCN;QSOX1;Q6;QSCN6;UNQ2520;PRO6013;quiescin sulfhydryl oxidase 1

Research Areas:Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;FCM;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A348

UNIProt ID:O00391

Accession:

Background:QSOX1 belongs to the family of FAD-dependent sulfhydryl oxidases and is an atypical disulfide catalyst. QSOX1 is mainly located in the Golgi apparatus and endoplasmic reticulum (ER) in human embryonic fibroblasts, and it cooperates with protein disulfide isomerase (PDI) to help fold new-born proteins in the cell. QSOX1 is mainly expressed in the heart, placenta, lung, liver, skeletal muscle, and pancreas, and is very weakly expressed in the brain and kidneys. Studies have found that the increase of QSOX1 expression in tumor cells enables tumor cells to actively circumvent the mechanism of apoptosis mediated by reactive oxygen species.

Concentration:1 mg/mL

Immunogen:Recombinant human QSOX1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;FCM 1:100;IP 1:25-1:50

Calculated MW:83 kDa

ObservedMW:67 kDa